期刊文献+

HPLC法考察注射用泮托拉唑钠的配伍稳定性 被引量:4

下载PDF
导出
摘要 目的:考察注射用泮托拉唑钠与3种常用输液配伍稳定性。方法:应用HPLC法测定药物配伍后6h泮托拉唑的含量,同时观察外观变化及测定pH值。结果:注射用泮托拉唑钠与0.9%生理盐水配伍6h较稳定,而与5%葡萄糖及10%葡萄糖配伍时分别出现纤维状物、变色最后浑浊。结论:注射用泮托拉唑钠与0.9%生理盐水可以配伍稳定,不能与5%葡萄糖及10%葡萄糖注射液配伍使用。
出处 《黑龙江医药科学》 2011年第5期69-70,共2页 Heilongjiang Medicine and Pharmacy
  • 相关文献

参考文献4

二级参考文献12

  • 1王东凯,房芳,缪硕宁,任吉霞,祁静,徐亚杰,郭雅丽.高效液相色谱法测定潘妥拉唑血浆浓度[J].沈阳药科大学学报,1996,13(4):246-250. 被引量:1
  • 2刘胜.新型质子泵抑制剂潘妥拉唑的药理与临床[J].中国药房,1997,8(3):133-134. 被引量:6
  • 3Ekpe A,Jacobsen B.Effect of various salts on the stability of lansoprazole, omeprazole, and pantoprazole as determined by high-performance liquid chromatography[J ]. Drug Dev Ind Pharm, 1999,25(9): 1 057.
  • 4Lew EA,pisegna JR,star JAet al.Intravenous pantoprazole rap-idly controls gastric acid hypersecretion in patients with[].Zollinger-Ellison Syndrome Gastroenterology.2000
  • 5Chikawa T,Ishihara,Saigenjik.Effect of acid-inhibitory antiulcer druys on mucin biosynthesis in the rat stomach[].European Journal of Haematology.1994
  • 6Barkun A,Bardou M,Marshall JK.Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding[].Annals of Internal Medicine.2003
  • 7Metz DC.Potential uses of intravenous proton pump inhibitors to control gastric acid secretion[].Digestion.2000
  • 8Shin JM,Besan con M,Simon A,et al.The site of action of pantoprazole in the gastric H+-K+-ATPase[].Biochimica et Biophysica Acta.1993
  • 9Mctavish D,Buckley M,Hell KC.Omeprazole: An update review of itspharmacology and therapeutic use in acid- related disorders[].Drugs.1991
  • 10Patchett SE,O’Donoghue DP.Pharmacological manipulation of gastric juice: thrombelastographic assessment and implication for treatment of gastrointetsinal haemorrhage[].Gut.1995

共引文献47

同被引文献28

引证文献4

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部