温阳健脾化湿治疗慢性萎缩性胃炎疗效评价

Efficacy of Wenyangjianpihuashi on Treating Chronic Atrophic Gastritis

目的:研究和评价温阳健脾化湿治疗慢性萎缩性胃炎(CAG)的疗效并探讨其机理。方法:经中医辨证论治分为温阳健脾组、清热化湿组和对照组,进行相应的治疗,检测各组治疗前后血清表皮生长因子(EGF)水平变化和治疗前后症状和病理变化进行对比分析。结果:治疗组经治疗后血清EGF含量明显下降(P<0.01),对照组治疗后血清EGF变化不大,治疗组的临床症状和病理变化也明显改善(P<0.01)。结论:温阳健脾、清热化湿法结合西医常规治疗方法能提高疗效,值得研究和推广。

Objective： To research the mechanism of Wenyangjianpihuashi on treating chronic atrophic gastritis and evaluate its efficacy.Methods： Patients were divided into Wenyangjianpi group,Qingrehuashi group and control group by Chinese medical treatment,the changes of epithelial growth factor（EGF）,symptom and pathology were tested between pro-and post-treatment.Result： EGF level was decreased significantly in treating group compared with control group（P0.01）,symptom and pathology were changed significantly in control group too（P0.01）.Conclusion： The method of Wenyangjianpi and Qingrehuashi combined with western medicine can improve the efficacy of treating chronic atrophic gastritis.Deep research and popularization are valuable.