红景天苷及其类似物合成研究进展

Development in synthesis of the salidroside and its analogues

红景天苷为景天科植物红景天的主要活性成分。研究发现,红景天苷具有抗缺氧、抗疲劳、抗微波辐射、兴奋中枢神经和调节内分泌等药理活性,由于其结构简单,毒性小,广泛的药理活性而倍受人们的关注。笔者从化学合成和生物合成两个方面对红景天苷及其类似物的合成进行了综述。

Salidroside, was known as the main bioactive component in the root of Rhodiola sachalinensis A Bor and was reportedto have many pharmacological properties such as resisting anoxia, fatigue and microwave radiation, excited nervous system and endocrine regulation..Because of its simple chemical structure, less toxicity, wide range of pharmacological activity and got much attention. In this paper, Chemical synthesis and biosynthesis from two aspects of salidroside and its analogues are reviewed.