期刊文献+

家族性高胆固醇血症青少年早发冠心病3例 被引量:4

下载PDF
导出
摘要 冠心病随着年龄增加罹患风险增加,过去常被认为是老年性疾病,近年来,随着生活条件的提高和生活方式的改变,发病年龄有年轻化趋势,但多数病人均伴有肥胖、高血压、吸烟、糖尿病或家族史等危险因素。无上述因素的青少年发病仍属少见,家族性高胆固醇血症(familialhypereholesterolemia,FH)是非常值得重视的原因之一,本文报道3例。
出处 《中国动脉硬化杂志》 CAS CSCD 北大核心 2011年第11期949-951,共3页 Chinese Journal of Arteriosclerosis
  • 相关文献

参考文献9

  • 1Mohammad Hassan Nemati, Behrooz Astaneh. Optimal management of familial hypercholesterolemia: treatment and management strate- gies[ J]. Vase Health Risk Manag, 2010, 6:1 079-088.
  • 2Relationship of atherosclerosis in young men to serum lipoprotein cholesterol concentrations and smoking. A preliminary report from the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group [ J],. JAMA,1990, 264:3 018-024.
  • 3Forster LF, Stewart G, Bedfont D, et al. Influence of atrovastatin and simvastatin on apolipoprotein B metabolism in moderate com- bined hyperlipidemic subjects with low VLDL and LDL fractional clearance rates[ J]. Atherosclerosis, 2002, 164( 1 ) : 129-145.
  • 4Miida T, Nakamura Y, Okada M. Development of coronary athero- sclerosis in a symptomatic heterozygous patients with familial hyper- cholesterolemia[J]. J Cardiol, 1996, 28(2) : 71-77.
  • 5Hamilton-Craig I, Kostner K, Colquhoun D, et al. Combination therapy of statin and ezetimibe for the treatment of familial hyper- cholesterolemia[ J]. Vasc Health Risk Manag, 2010, 6:1 023- 037.
  • 6de Jongh S, Lilien MR, opt Roodt J, et al. Early statin therapy re- stores endothelial function in children with familial hypercholesterol- emia[J]. J Am Coll Cardiol, 2002, 40:2 117-121.
  • 7Wiegman A, Hutten BA, de Groot E, et al. Efficacy and safety of statin therapy in children with familial hypercholesterolemia[ J]. JA- MA, 2004, 292: 331-337.
  • 8Daniel SR, Greer FR. Committee on Nutrition: lipid screening and cardiovascular health in childhood I J]. Pediatrics, 2008, 122: 198-208.
  • 9de Ferranti S, Ludwig DS. Storm over statins-the controversy sur- rounding pharmacologic treatment of children [ J ]. N Eng J Med, 2008, 359:1 309-312.

同被引文献62

  • 1杨永宗.动脉粥样硬化实验研究模型百年回溯[J].中国动脉硬化杂志,2008,16(12):925-927. 被引量:5
  • 2黎荣山,杨进,银剑斌,陈世忠,陈慧.家族性高胆固醇血症并发急性心肌梗死1例[J].广西医科大学学报,2010,27(6):983-984. 被引量:3
  • 3王爱玲,徐岩,程景林.20岁青年家族性高胆固醇血症合并心肌梗死一例[J].中华心血管病杂志,2006,34(1):80-81. 被引量:5
  • 4陆宗良.脂质代谢异常与冠心病[M].北京:人民军医出版社,1998,77.
  • 5Fahed AC, Nemer GM. Familial hypercholesterolemia: the lipids or the genes? [ J]. Nutr Metab, 2011, 22, 8 (1): 23.
  • 6Van Craeyveld E, Gordts SC, Nefyodova E, et al. Regres- sion and stabilization of advanced murine atherosclerotic le- sions : a comparison of LDL lowering and HDL raising gene transfer strategies [J]. J Mol Med, 2011, 89 (6): 555-567.
  • 7Hibbitt O, Agkatsev S, Owen C, et al. RNAi-mediated knockdown of HMG CoA reductase enhances gene expres- sion from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo[ J]. Gene Ther, 2012, 19(4) : 463-467.
  • 8Forrest LM, Boudyguina E, Wilson MD, et al. Echium oil reduces atherosclerosis in ApoB100-only LDLrKO mice [J]. Atheroselerosis, 2012, 220(1): 118-121.
  • 9Ishibashi S, Brown MS, Goldstein JL, et al. Hypercholes- terolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery [ J ]. J Clin Invest, 1993, 92 (2) : 883-893.
  • 10/ Jawiefi J, Nasta|ek P, Korbut R. Mouse models of experi / mental atherosclerosis [ J]. J Physiol Pharmacol, 2004, 5 / (3) : 503-517.

引证文献4

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部