摘要
[目的]采用正交实验优选清脑镇静颗粒的最佳处方。[方法]以颗粒剂吸湿率为指标,采用正交设计实验,对处方配比进行筛选[。结果]优化处方为:干浸膏粉∶糊精∶乳糖∶微晶纤维素=10∶2∶3∶2。优化后清脑镇静颗粒吸湿率较中药浸膏粉有明显降低。[结论]清脑镇静颗粒剂处方合理、工艺可行,符合颗粒剂的质量要求。
[Objective] To optimize the prescription for Qingnao Zhenjing granules by orthogonal design.[Methods] Moisture rate as an index,in order to optimize the dosage and ultimately determine the prescription,the orthogonal experimental design was used.[Results] The optimizing prescription contains ：extracts powder： dioxide ∶ lactose ∶ microcrystalline cellulose=10∶2∶3∶2.[Conclusion] The optimized prescription and technology is reasonable,and conform to the quality requirements of granules.
出处
《天津中医药》
CAS
2011年第5期421-423,共3页
Tianjin Journal of Traditional Chinese Medicine
基金
国家科技支撑计划项目(2007BAI41B06)
关键词
清脑镇静颗粒剂
正交实验
吸湿率
处方优化
Qingnao Zhenjing granules
orthogonal design
moisture rate
optimization of prescription
