电针干预对糖耐量受损患者血糖的影响

Intervention of electroacupuncture for patients with impaired glucose tolerance

目的:探讨电针干预对糖耐量受损(IGT)患者餐后2 h血糖水平的调节作用。方法:将60例糖耐量受损患者随机分为电针组、空白对照组,每组30例。电针组采用电针肾俞、脾俞、足三里、三阴交的干预方法,刺激干预6个疗程;空白对照组未做干预。观察患者电针干预前后及空白对照组同期空腹血糖(FBG)、75 g葡萄糖负荷2 h后血糖(2h PBG)、糖化血红蛋白(HbA1c)水平及疗效。结果:电针组进行6个疗程的电针干预后,总有效率为76.7%(23/30),明显优于空白对照组的16.7%(5/30),P<0.01,并可显著降低2h PBG[(7.08±0.74)mmol/L]及HbA1c[(5.74±0.35)%],疗效明显优于空白对照组[(8.93±1.87)mmol/L、(5.97±0.591)%],差异有统计学意义(P<0.01,P<0.05),并对患者正常的FBG水平不造成影响。结论:电针干预可以作为IGT人群的临床有效干预方法及糖尿病早期防治手段。

Objective To explore the regulation on 2-hour postprandial blood glucose （2h PBG） for patients with impaired glucose tolerance （IGT） in the intervention with electroacupuncture. Methods Sixty cases of IGT were divided randomly into an electroacupuncture group and a blank control group, 30 cases in each one. In elec troacupuneture group, electroacupuncture was applied to Shenshu （BL 23）, Pishu （BL 20）, Zusanli （ST 36） and Sanyinjiao （SP 6） in the intervention, lasting for 6 sessions. In blank control group, no any intervention was a- dopted. The levels of fasting blood-glucose （FBG）, 2 h PBG with 75 g glucose and hemoglobin Alc （HbAlc） were observed before and after the intervention for the patients in electroacupuncture group, as well as in blank control group. Results The total effective rate was 76.7% （23/30） in electroacupuneture group, which was superior to that of 16.7% （5/30） in blank control group （P〈0. 01）. 2h PBG [-（7.08±0. 74）mmol/L] and HbAle [（5.74±0.35）%] were down-regulated significantly after the intervention with electroacupuncture of 6 sessions in electroacupuncture group. The therapeutic effects of it were superior remarkably to those [-（8. 93 ± 1.87 ） mmol/L, （5.97 ± 0. 591 ） %] in blank control group, indicating statistical significant difference （P〈0.01, P〈0. 05）. But, there was no any impact for the patients with normal FBG. Conclusion Electroacupuneture may be the means to achieve the clinical effective intervention for the people with IGT and the approach in the prevention and treatment of diahetes at the early stage.