深圳市居民血脂异常流行病学调查

Prevalence of dyslipidemia among residents of Shanzhen city

目的了解广东省深圳市15～69岁居民血清胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白(HDL-C)的流行水平及分布特征,为心血管疾病预防提供依据。方法按照分层随机抽样原则随机抽取深圳市73个社区,共8 751名15～69岁居民进行入户调查、体格检查和血脂测定。结果深圳市15～69岁居民TC、TG、HDL-C水平分别为4.86,1.57和1.23 mmol/L;TC和TG水平男性高于女性(P<0.05),随着年龄的增加而上升(P<0.05);血脂异常患者3 568例,标化患病率38.08%,其中高TC、高TG和低HDL-C患者1 621,2 461和920例,标化患病率分别为17.22%,25.72%和10.65%,深圳市居民血脂异常类型主要为高TG型;血脂异常患病率男性高于女性(P<0.05),高TC和高TG患病率均随着年龄的增长有上升趋势(P<0.05),并具有阶段性特点;心血管病危险因素在血脂异常患者中有聚集现象。结论深圳市居民血脂异常患病率高,控制人群血脂水平,可降低心血管疾病的发生。

Objective To study the distribution characteristics of plasma total cholesterol（TC）,triglyceride（TG）,high-density lipoprotein cholesterol（HDL-C） levels,and dyslipidemia among the residents aged form 18 to 69 years in Shenzhen city. Methods Totally 73 communities and 8 751 residents were sampled through stratified randomized sampling and the information of the residents was collected by questionnaire survey,physical examination and laboratory tests. Results The levels of TC,TG and HDL-C were 4.86 mmol/L,1.57 mmol/L,and 1.23 mmol/L,respectively.The TG and TC in the males were higher than in the females（P0.05） and increased with age（P0.05）.Among the partcipants,3 568 had dyslipidemia（38.08%） and the rates of high TG,high TG,and low HDL-C were 17.22%,25.72%,and 10.65%,respectively.The main type of dyslipidemia was high TG.The prevalence of dyslipidemia was higher for female（P0.05） and the prevalence of high TC increased with age（P0.05）.There existed aggregation of risk factors among the participants with dyslipidemia. Conclusion High prevalence of dyslipidemia in Shenzhen city was found.Control of lipid levels within normal range may prevent the occurrence of cardiovascular disease.