感染旋毛虫兔血嗜酸性粒细胞计数的动态变化

Dynamic variation of eosinophil count in rabbits infected with Trichinella Spiralis

目的观察旋毛虫感染兔后血嗜酸性粒细胞的动态变化,为旋毛虫病(Trichinosis)血嗜酸性粒细胞的检测提供基础资料。方法将实验用兔随机分组:感染组10只,每只喂入10 000条幼虫;对照组10只。在感染后不同时间检测血嗜酸性粒细胞绝对数。结果感染旋毛虫兔血嗜酸性粒细胞计数升高,于第4周达高峰,随后逐渐降低。结论嗜酸性粒细胞的检测对于旋毛虫病具有辅助诊断意义。

Objective To observe the dynamic change of eosinophil count in rabbits infected with Trichinella spiralis so as to offer basic data for eosinophil examination in trichinosis.Methods Experimental rabbits were divided into two groups each consisted of 10 rabits.The rabbits in infected group were inoculated by gavage with 10 000 Trichinella spiralis larvae,10 rabbits in control group.The blood samples were obtained from rabbits in the two group at different time after infection,the eosinophil absolute count was determined.Results The eosinophil absolute count in infected group raised and reached peak on the fourth week after infection and then began to decline therafter.Conclusions The detection of eosinophil examination has assistant values in diagnosis of trichinosis.