丙泊酚复合曲马多进行人工流产的临床观察

Study of propofol combined with tramadol for analgesia of induced abortion

目的观察丙泊酚复合曲马多进行无痛人工流产(以下简称人流)的效果。方法选择自愿终止妊娠妇女90例随机分为3组,每组各30例,对照组,丙泊酚组和丙泊酚曲马多组。丙泊酚曲马多组术前先给予曲马多1mg/kg静脉注射,1min后再静脉给予丙泊酚2mg/kg,丙泊酚组按2.5mg/kg静注,对照组术中不用任何镇静镇痛药。观察手术中及术后疼痛、生命体征、手术时间及人流综合症等情况。结果丙泊酚组和丙泊酚曲马多组的麻醉效果显著优于对照组(P<0.05)。丙泊酚组和丙泊酚曲马多组的术后镇痛效果显著优于对照组(P<0.05)。丙泊酚曲马多复合麻醉能减少麻醉药的用量。结论丙泊酚曲马多复合麻醉具有良好的镇静、镇痛作用,可保持心血管功能稳定,减少麻醉药的用量,预防人流综合症的发生。

Objective To study the feasibility and safety of propofol combined with tramadol for analgesia of induced abortion.Methods Ninety pregnant women were divided into three groups.Tramadol and propofol group was given propofol combined with tramadol for anesthesia,including tramadol 1mg/kg intravenous infusion and propofol 2mg/kg intravenous injection.Propofol group was given propofol 2.5mg/kg intravenous injection.Effects of analgesia and anaesthesia and side effects were recorded.Results The effects of anaesthesia in propofol group and tramadol group were better than those of control group.The effects of postoperation analgesia in tramadol group was better than that of propofol group.The use of tramadol can reduce the dosage of propofol.Conclusions Propofol combined with tramadol for analgesia of induced abortion has good effect and is suitable for outpatient,with features of simplicity,safety,reliability and less complications.