本院非麻醉科2008—2010年麻醉性镇痛药临床应用分析

Application analysis of narcotic analgesics used in our hospital except anesthesiology department during period from 2008 to 2010

目的分析本院2008年至2010年非麻醉科麻醉性镇痛药的应用现状和趋势,促进临床合理用药。方法采用频度分析记录本院门急诊及病房2008年至2010年麻醉性镇痛药(不包括麻醉科)的使用情况,统计药名、规格、用量、总用药量和用途等内容,计算用药频度(DDDs),分析用药情况。结果常用麻醉性镇痛药有吗啡缓释片、芬太尼透皮贴剂、羟考酮控释片和哌替啶注射液等,主要用于晚期癌痛、术前及术后止痛。门诊和病房吗啡缓释片的DDDs排名第一,急诊DDDs排序中哌替啶注射液名列第一,其次为布桂嗪注射液和吗啡注射液。结论本院对疼痛患者三阶梯止痛药的应用基本合理,但作为止痛标尺的吗啡的用量远没达到发达国家的水平,应进一步落实"三阶梯止痛治疗方案",提高疼痛患者生活质量。

AIM To evaluate the application status and tendency of narcotic analgesics used in our hospital except anesthesiology department during the period from 2008 to 2010, and in an effort to provide guidance for rational medication. METHODS The use of three-stage analgesics for patients during the period from 2008 to 2010 in our hospital except anesthesiology department was analyzed statistically in respect to consumption sum, DDDs and average daily costs, etc, using frequency analytical method. RESULTS The commonly used analgesics were morphine sustained-release tablets, fentanyl transdermal system, oxyeodone controlled-release tablets and pethidine injection which were used for patients with cancer or during perioperative period. The DDDs of morphine injection dominated the first place for outpatient and inpatient. Pethidine injection was the first place, and then bucinnazine injection and morphine injection were the second and the third place for emergency department. CONCLUSION The use of three-stage analgesics for patients with pain in our hospital is rational on the whole, yet the application of three-stage analgesic therapy for pain relief in patients should be further publicized in order to improve the quality of patients＇ life.