组织多普勒超声评价原发性醛固酮增多症患者心脏结构和功能改变

Evaluation of cardiac structure and function changes with tissue Doppler echocardiography in primary aldosteronism patients

目的:探讨利用组织多普勒超声评价原发性醛固酮增多症患者的心脏结构和功能改变。方法:对于18例确诊的原发性醛固酮增多症、20例单纯性高血压和15例健康志愿者进行组织多普勒超声检查,比较各组之间心脏结构及左室收缩、舒张功能的改变。结果:原发性醛固酮增多症患者LA、LVEDd、IVSd、LVPWd、LVMI、E/Em明显增高,Em/Am低于对照组,LVEF与对照组及单纯高血压组差异无统计学意义。结论:原发性醛固酮增多症患者左室腔内径及左室壁厚度增加,组织多普勒超声可以检出早期左室舒张功能减低患者。

Objective To evaluate the cardiac structure and function changes by tissue Doppler echocardiography examination in primary aldosteronism patients.Method Eighteen aldosteronism patients,20 essential hypertension patients and 15 healthy controls underwent conventional and tissue Doppler echocardiography examination.Cardiac structure and function were evaluated between the three groups.Results Primary aldosteronism patients showed a larger LA,LVEDd,ISVd,LVPWd,LVMI and E/Em than the control group,and Em/Am was significantly lower than the control group.There was no significant difference between primary aldosteronism patients,the control group and essential hypertension patients in LVEF.Conclusion A larger left ventricular inside diameter and left ventricular wall thickness are found in the patients with primary aldosteronism,and early left ventricular diastolic dysfunction can be detected with tissue Doppler echocardiography.