维药胡萝卜子质量标准研究

Research on quality specification of Daucus carota seed

目的:建立维药胡萝卜子的质量控制标准,为其临床安全、可控应用提供科学依据。方法:于不同产地采集10批胡萝卜子样品,对其原植物进行鉴定,对其性状进行鉴别,对粉末进行显微鉴别;测定10批胡萝卜子药材的杂质、水分、总灰分、酸不溶性灰分、浸出物;测定10批胡萝卜子药材的挥发油含量。结果:对胡萝卜子药材的来源、性状进行了描述,对粉末显微进行了鉴别;检查项中暂定胡萝卜子药材杂质不得过3.0%,水分不得过11.0%,总灰分不得过21.0%,酸不溶性灰分不得过6.0%,浸出物不得少于5%;根据挥发油测定结果暂定本品挥发油含量不得少于0.50%(mL/g)。结论:所制定胡萝卜子药材的质量控制标准可用于评价胡萝卜子药材的质量。

Objective： To provide scientific basis for clinical safety and control applications by establishing the quality control specification of Daucus carota seed.Methods： Collected Daucus carota seed samples in 10 batches of different origins,identified its original plant,described its characteristics and took microscopic identification of the powder;Determined the impurities,moisture,total ash,acid-insoluble ash and extract of these 10 batches Daucus carota seeds 2010 version（Vol Ⅰ） of appendix Ⅸ H and K and The essential oil determination method of Daucus carota seed and the essential oil determination method of Daucus carota seed according to Chinese Pharmacopoeia.Results： The origins,macroscopic and microscopic identification of Daucus carota seed are described,temporarily formulating impurities shall not exceed 3.0%,moisture shall not exceed 11.0%,total ashes shall not exceed 21.0%,acid-insoluble ashes shall not exceed 6.0%,extract shall not less than 5.0%.Determine the essential oil of Daucus carota shall not less than 0.50%（mL/g）.Conclusion： The Daucus carota seed quality control standard can be used to evaluate the quality of Daucus carota seed.