脑内巨大海绵状血管瘤

Analysis on cerebral giant cavernous malformation

目的探讨脑内巨大海绵状血管瘤(GCM)的临床特点及治疗。方法回顾性分析3例脑内巨大海绵状血管瘤的临床资料。结果 3例患者中,2例行手术治疗,完整切除病变,术后均无神经功能障碍及其他严重并发症,1例术后原有头痛完全缓解,视力、视野部分恢复;1例术后发作完全控制;1例拒绝手术,随访2年仍有癫(?)发作,尚未出现较严重卒中事件。结论脑内巨大海绵状血管瘤应作为一项分类诊断独立出来。"直径≥6cm"的标准比较方便临床诊断和治疗的判断。一经MRI、CT确诊,手术应尽早实施。病变的完全切除将获得令人满意的预后。

Objective To explore the clinical characteristics and treatment of cerebral giant cavernous malformation （GCM）. Methods The clinical data of three patients with cerebral CA were analyzed retrospectively. Results Of 3 patients, 2 received operation of complete lesion excision. No neurological deficit or other serious complications occurred in 2 patients after operations. One of the 2 patients had experienced headache before operation but was eased afterwards. Besides, his vision and visual field partially recovered. The other one was seizure free after surgery. One patient who refused surgery was found to have seizures during the two-year tbllow-up, but no serious hemorrhage event. Conclusions Hence, the diagnosis of cerebral giant cavernous malformation should be regarded as an independent one. The criterion of “diameter≥6cm” is more convenient for the clinical diagnosis and measures. A surgery ought to be applied in time once the patient is diagnosed by MRI and CT. A complete lesion excision can bring about satisfactory prognosis.