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脐带源间充质干细胞脑室内移植治疗脑瘫的临床观察 被引量:1

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摘要 目的:观察脐带源间充质干细胞移植对脑瘫的治疗效果。方法:对脑瘫患者在脑室额角穿刺行第一次干细胞移植,将硅胶导管预留置头皮下行第二次移植,1周后自此将干细胞移植到脑室;观察语言、肌力、肌张力改善程度。结果:经干细胞移植术后,患者肌张力高症状及姿势异常均有所改善,肌力提高1级,语言功能有所改善。结论:脐带源间充质干细胞移植对脑瘫有治疗效果。
出处 《医学信息(下旬刊)》 2011年第10期100-100,共1页 Medical information
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  • 1中华人民共和国国务院.医疗机构管理条例.1994-09-01.[2006-08-01].http://www.gov.cn/banshi/2005-08/01/content_19113.htm
  • 2Kanemura Y. Development of cell - processing systems for human stem cells (neural stem cells, mesenchymal stem cells, and iPS cells) for re- generative medicine. Keio J Med. 2010 ;59 (2) :35 -45.
  • 3Buhnemann C, Scholz A, Beroreuther C, et al. Neuronal differentiation of transplanted embryonic stem cell - derived precursors in stroke lesions of adult rats. Brain. 2006 : 129 (12) : 3238 - 3248.
  • 4Pignataro G, Studer FE, Wilz A, et al. Neuroprotection in ischemic mouse brain induced by stem ceil - derived brain implants. J Cereb Blood Flow Metab. 2007 ;27 (5) :919 - 927.
  • 5Harris DT. Cord blood stem cells : a review of potential neurological appli- cations. Stem Cell Rev. 2008 ;4(4) :269 -74.
  • 6Tao YX, Xu HW, Zheng Q Y, etal. Noggin induces human bone marrow - derived mesenchymal stem ceils to differentiate into neural and photore- ceptor cells. Indian J Exp Biol. 2010 May;48(5) :444 -52.
  • 7Liao W, Zhong J, Yu J, etal. T'erapeutic bene&it of human umbilical cord derived mesenchymal stromal ceLls in intracerebral Hemorrhage rat: implications of anti - inflammation and angiogenesis. Cell Physiol Bio- chem. 2009;24(3 -4) :307 - 16.
  • 8Chen A, Siow B, Blamire AM, et al. Transplantation of magnetically la- beled mesenchymal stem cells in a model of perinatal brain injury. Stem Cell Res. 2010 ;5(3) :255 -66.
  • 9杜侃,栾佐,屈素清,刘卫鹏,汪兆艳,杨印祥,杨辉.骨髓间充质干细胞移植治疗小儿重度脑性瘫痪的疗效观察[J].临床儿科杂志,2011,29(1):55-58. 被引量:16
  • 10吴芳,杨万章,张敏,杨佳勇,盛佑祥,赵宁,梁豪文,唐映.脑瘫患儿应用脐血间质干细胞的临床安全性研究[J].中西医结合心脑血管病杂志,2008,6(12):1405-1406. 被引量:9

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  • 1施炳培,李惠,卜怀娣,侍孝娟,王素娟,史惟,杨红.穴位注射治疗小儿脑性瘫痪精细运动功能障碍57例疗效观察[J].中国康复理论与实践,2006,12(2):105-106. 被引量:20
  • 2王子才,姜志梅.中国康复医学会第2届儿童康复学术会议 中国残疾人康复协会 第9届小儿脑瘫康复学术会议暨国际交流会议[J].实用儿科临床杂志,2006,21(24):1742-1742. 被引量:141
  • 3Ramasamy S,Narayanan G,Sankaran S, et al.Neural stem cell survival factors. Arch Biochem Biophys.2013; 534(1-2):71-87.
  • 4Yang K,Han S,Shin Y, et al.A microfluidic array for quantitative analysis of human neural stem cell self-renewal and differentiation in three-dimensional hypoxic microenvironment. Biomaterials. 2013;34(28):6607-6614.
  • 5Piltti KM, Salazar DL, Uchida N,et al. Safety of human neural stem cell transplantation in chronic spinal cord injury.Stem Cells Transl Med.2013;2(12):961-974.
  • 6Vargus-Adams JN, Martin LK, Maignan SH, et al. The GMFM,PEDI, and CP-QOL and perspectives on functioning from children with CP, parents, and medical professionals.J Pediatr Rehabil Med.2011;4(1):3-12.
  • 7贺力男,孟祥琨,赵廷宝.脐带间充质干细胞治疗痉挛性脑瘫1例临床分析[J].医学信息,2012,25(11) 80-81.
  • 8陶其强,唐明淇,许冬联,等.脐带血干细胞治疗小儿脑性瘫痪10例近期疗效分析[J]. 中外健康文摘,2009,6(35):18-19.
  • 9De Feo D, Merlini A, Laterza C,et al.Neural stem cell transplantation in central nervous system disorders: from cell replacement to neuroprotection.Curr Opin Neurol. 2012;25(3): 322-333.
  • 10Russell DJ,Palisano RJ,Walter S, et al. Evalrating motor function in children with down syndrome:validity of the GMFM.Dev Med Child Neurol.1998; 40(10):693-701.

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