氨溴索辅助治疗老年社区获得性肺炎的临床疗效观察

Ambroxol adjuvant treatment of elderly community - acquired pneumonia clinical observation

目的：观察探讨氨溴索辅助治疗老年社区获得性肺炎的临床疗效，总结其临床价值。方法：选取我院2007年4月至2010年8月300例社区获得-挂肺炎的老年患者，随机分为观察组和对照组，各150例。对照组采用常规治疗，观察组在常规治疗的基础上加用氨溴索辅助治疗。观察对比两组治疗效果，记录相关数据进行统计学分析。结果：观察组痊愈72例，显效50例，有效25例，无效3例，总有效率81．3％，对照组痊愈48例，显效51例，有效23例。无效28例，总有效率66．O％，两组疗效对比差异显著（P〈0．05），具有统计学意义。两组治疗前后IL-6、IL—10水平对比差异显著（P〈O．05）。具有统计学意义。结论：氨溴索辅助治疗老年社区获得性肺炎的临床疗效显著，明显优于常规治疗，能有效地促痰液排出，具有重要的临床应用价值。

Objective： To observe the adjuvant treatment of elderly ambroxol community - acquired pneumonia clinical efficacy, summarize its clinical value. Methods： A hospital from April 2007 to August 2010 300 cases of community - acquired pneumonia in elderly patients, randomly divided into two groups and the control group, of 150 patients in the control group with conventional therapy, the observation group in the conventional treatment based plus adjuvant therapy with ambrexol, observed and compared two groups of treatment, record the data for statistical analysis. Results： The cured 72 cases, effective in 50 cases, effective in 25 eases, 3 cases, the total efficiency of 81.3 % in the control group cured 48 cases, effective in 51 cases, effective in 23 cases, 28 cases, the total effective rate 66.0%, Comparative efficacy of two groups differ significantly （ P 〈 0.05 ）, with statistical significance. Before and after treatment IL - 6, IL - 10 levels contrast significantly different （P 〈 0.05 ）, with statistical significance. Conclusions： Ambroxol adjuvant treatment of elderly community -acquired pneumonia clinical effect is significant, clearly superior to conventional therapy, can effectively promote mucus discharge, has important clinical value.