病理技术在先天性巨结肠诊断中的研究应用进展

先天性巨结肠，是儿童较为常见的一种疾病，其主要病理表现为结肠远端的神经节细胞的完全缺乏，病变肠断持续的痉挛狭窄，造成了病变段以上的肠管出现了代偿性的扩张，肠壁增厚，进而形成巨结肠。患者多出现有部分性或者完全性的结肠肠梗阻。采用病理技术对先天性巨结肠进行诊断。主要是为了准确地将神经节细胞分辨出来，进而协助医生对巨结肠进行判断。本文从常规的病理染色、乙酰胆碱酯酶染色、免疫组织化学染色等，综述病理技术在先天性巨结肠诊断中的应用价值。

Hirschsprung＇s disease is more common a disease of children, the main pathological manifestations of the distal colon, a complete lack of ganglion cells in the lesion heartbroken sustained spasm narrow, resulting in lesions of the bowel segment appeared in more than compensatory expansion , wall thickening, and thus the formation of giant colon. Often seen in patients with partial or complete obstruction of the colon. Pathological techniques used for diagnosis of Hirschsprung＇s disease, mainly in order to accurately tell the difference ganglion cells, and thus help doctors judge the giant colon. In this paper, the conventional pathological staining, acetylcholinesterase staining, immunohistochemical staining, etc. , reviewed pathology technology in the diagnosis of Hirschsprung＇s application.