肺源性心脏病患者胰岛素抵抗的临床研究

Research on insulin resistance in patients with palmonary heart disease

目的探讨肺源性心脏病急性期患者胰岛素抵抗的规律。方法分别采用葡萄糖氧化法和酶联免疫吸附试验(ELISA)法对肺源性心脏病患者组和对照组的空腹血糖(FPG)和空腹血清胰岛素(FINs)进行测定。结果肺源性心脏病患者组FPG和FINs均高于对照组,而胰岛素敏感性指数(ISI)低于对照组。结论肺源性心脏病急性期患者存在胰岛素抵抗,对此类患者应考虑使用胰岛素增敏剂治疗。

Objective To explore the insulin resistance pattern of patients with pneumocardial disease. Methods The fasting plasma glucose （FPG） and fasting insulin （FINs） in the patients with pneumocardial disease and patients in control group were detected with glucose oxidase assay and enzyme-linked immunosorbent assay （ELISA）. Results The contents of FPG and FINs in the patients with pneumocardial disease were higher than that in the patients of control group, and the insulin sensitivity index in the patients with pneumocardial disease was lower than that in the patients of control group. Conclusion The patients with pneumocardial disease have insulin resistance, and insulin sensitizers considered should be used in these patients.