农村成年人群代谢综合征16种类型的患病情况分析

Ethnic-and Sex-specific Prevalence of All 16 Risk Factor Combinations in Metabolic Syndrome

目的评估代谢综合征（MetS）不同类型在宁夏农村地区成年人群中的患病情况,比较其在回、汉族间及男女性别间的差异。方法采用横断面调查研究方法和整群抽样的方法,从固原市和吴忠市分别随机抽取回族和汉族自然村各1个,共4个自然村;调查样本量为2000人。自制问卷,调查对象的一般情况、身高、体重、体质指数（BMI）、血压（BP）,检测血清总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）。结果共调查1612人（25~74岁,40.2%女性）。成年人群中发生频率最高的MetS类型：汉族BMI＋HDL-C＋BP（3.4%）,回族BMI＋TG＋BP（4.7%）。女性的HDL-C＋BP＋FPG和BMI＋HDL-C＋FPG患病率高于男性（1.7%vs 0.9%,2.5%vs 1.0%）。回族成年人群中,女性BMI＋TG＋HDL-C、BMI＋BP＋FPG和BMI＋HDL-C＋FPG的患病率高于男性（1.4%vs 0,5.0%vs 1.5%,2.8%vs 0.8%）。回族女性BMI＋TG＋BP＋FPG、BMI＋BP＋FPG和BMI＋TG＋FPG的患病率高于汉族女性（2.4%vs 0.7%,5.0%vs 2.6%,4.0%vs 1.5%）。结论农村回族和汉族MetS 16种类型的分布不同,但超重或肥胖、血脂异常和高血压在MetS中的表现是相似的;回族女性MetS主要表现为空腹血糖受损、糖耐量受损和糖尿病的可能性要高于汉族女性。

Objective To assess the prevalence of all 16 combination types of MetS and to analyze the impact of ethnic and gender on prevalence rates.Methods A cluster sampling method was used to select subjects from Hui ethnic village and Han ethnic village randomly.The contexts of survey included behavioral factors and body index,while blood samples were collected.Serum total cholesterol（TC） triglyceride（TG）,high-density lipid protein cholesterol（HDL-C）,low-density lipoprotein cholesterol（LDL-C） was measured.All data was analyzed by spss11.5 software package.Associations between categorical variables were tested by χ2 test,whereas differences between categorical,several biochemical and clinical factors were tested by the use of the T test.Results 1612 subjects（25~74 years,40.2% female） were enrolled in analysis.In Han ethnic group the combination with body mass index（BMI）,high density lipoprotein（HDL-C） and blood pressure（BMI＋HDL-C＋BP） was the most frequent combination（3.4%）,hoewever body mass index（BMI）,triglyceride（TG） and blood pressure（BMI＋TG＋BP） was the most frequent combination（4.7%） in Hui ethnic group.Prevalences of HDL-C＋BP＋FPG and BMI＋HDL-C＋FPG were higher in female than those in male（1.7% vs 0.9%,2.5% vs 1.0%）.In Hui ethnic group prevalences of BMI＋TG＋HDL-C,BMI＋BP＋FPG and BMI＋HDL-C＋FPG was higher in female than those in male（1.4% vs 0% and 5.0% vs 1.5%,2.8% vs 0.8%）.In women,prevalences of BMI＋TG＋BP＋FPG,BMI＋BP＋FPG and BMI＋TG＋FPG were higher in Hui ethnic group than those in Han ethnic group（2.4% vs 0.7%,5.0% vs 2.6%,4.0% vs 1.5%）.Conclusion Large variations were found in the prevalence of all 16 combination types.Overweight or obesity,abnormity of plasma lipid and hypertension were the key point between Hui and Han ethnic group.Results found that the risk of impaired fasting glucose was higher in Hui ethnic women than Han ethnic women in all 16 combination types of MetS.