经鼻持续正压通气治疗新生儿急性呼吸衰竭临床研究

The clinical study of nasal continuous positive pressure therapy on acute neonatal respiratory failure

目的观察经鼻持续正压通气(NCPAP)治疗新生儿急性呼吸衰竭的疗效。方法对收治的22例急性呼吸衰竭新生儿使用NCPAP治疗后疗效及转归进行分析。结果治疗有效19例,无效3例。应用NCPAP后PO2、PaCO2、pH、R、HR均有明显改善(P<0.05)。结论 NCPAP治疗新生儿呼吸衰竭有良好的治疗效果,可减少气管插管,减少机械通气,是一种简便、适宜的新生儿呼吸支持技术。

Objective To study the effects of nasal continuous positive airway pressure（NCPAP） therapy of neonatal acute respiratory failure.Methods Analyses on NCPAP＇s efficacy were made on 22 newborn infants with acute respiratory failure who were admitted from June,2009 to June,2010.Results NCPAP was effective in 19 cases and ineffective in 3 cases.After the application of NCPAP,PO2,PaCO2,pH,Rand HR were all significantly improved（P0.05）.Conclusions NCPAP therapy of neonatal acute respiratory failure has good therapeutic effect.It,can reduce tracheal intubation and mechanical ventilation.It is a simple and appropriate neonatal respiratory support technology