红外分光光度法鉴别吲哒帕胺片

Identification of indapamine tablets by infrared spectrophotometry

目的建立红外光谱法鉴别吲哒帕胺片的方法。方法采用红外分光光度法,以丙酮为溶剂,对吲哒帕胺片中的吲哒帕胺进行提取,溴化钾压片,录制红外光谱图。结果吲哒帕胺片丙酮提取物的红外光谱图与吲哒帕胺对照品的红外光谱图一致,并与《药品红外光谱集》中吲哒帕胺的对照图谱一致。结论本方法专属性好,可快速、准确的鉴别本品。

OBJECTIVE To establish a rapid and exclusive method for the identification of Indapamine Tablets. METHODS The infrared spectrophotometry was adopted, in which the extract of Indapamine tablet was carried out with the Acetone as the solvent and with spectral purity potassium bromide tabletting as the infrared absorption spectrum. RESULTS The infrared absorption spectrum of the Indapamine Tablets was completely in conformity with that of the control substance and the standard spectrum of Indapamine issued in Infrared Spectrum Album of Drugs. CONCLUSION This method is specific, fast and accurate, which can be used for the identification of Indapamine Tablets.