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琥珀酰明胶预扩容预防硬膜外麻醉下剖宫产术低血压效果观察 被引量:2

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摘要 目的观察琥珀酰明胶预扩容预防硬膜外麻醉下剖宫产术低血压效果观察。方法选择120例在硬膜外麻醉下剖宫产术的患者.随机分为两组(n=60),麻醉后以25mL/(h·kg)的速度分别静脉输入琥珀酰明胶(I组)和乳酸钠林格氏液(Ⅱ组),此后均以10~15mL/(h·kg)的速度输入乳酸钠林格氏液。麻醉手术中间隔5min测量血压。取麻醉前(T0)、麻醉后5min(T1)、麻醉后10rain(T2)、麻醉后20min(T3)、麻醉后30min(T4)5个时间点,T0作为基础值,记录麻醉后及手术中各时点患者的血压、心率及发生恶心呕吐等反应、应用麻黄碱等情况。结果两组患者的SBP、DBP麻醉后10min均有所下降。与麻醉前相比无显著性差异(P〉0.05)。麻醉后20minII组SBP、DBP下降明显,与麻醉前、Ⅰ组相比差异有显著(P〈0.01)。Ⅰ组低血压发生率为6例(10%)。显著低于Ⅱ组33例(55%),恶心呕吐发生率.Ⅰ组7例(11.7%),Ⅱ组34侧(56.7%).Ⅱ组明显增多(P〈0.05)。结论琥珀酰明胶对硬膜外麻醉下剖宫产术的患者引起的低血压有很好预防作用。
出处 《海峡药学》 2011年第10期175-176,共2页 Strait Pharmaceutical Journal
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