阿奇霉素治疗小儿支原体肺炎66例临床观察

Clincal Analysis 66 Cases of Azithromycin on the Treatment of Pediatric Mycoplasma Pneumonia

目的:研究阿奇霉素治疗小儿支原体肺炎的临床效果。方法:对2009年1月-2010年11月我院入院治疗的132例小儿支原体肺炎患者进行了研究,随机分为两组,治疗组给药阿奇霉素,对照组给药红霉素,比较两组的治疗效果及临床不良反应。结果:治疗组治疗总有效率为93.9%,对照组总有效率为83.3%,两组比较差异明显,有统计学意义(P<0.05);对照组胃肠道反应等不良反应发生率明显高于治疗组,差异有统计学意义(P<0.05)。结论:阿奇霉素治疗小儿支原体肺炎临床疗效显著,不良反应少,好于第一代的红霉素,值得临床推广应用。

Objective： Study the clinical effect of azithromycin on the treatment of pediatric mycoplasma pneumonia. Methods： 132 children with mycoplasma pueumonia was investigated from Jan, 2009 to Nov, 2010. these children were divided into two groups, Treatment group was treated with azithromycin and control group with erythromycin. Compared efficacy and side effects. Results： Total effective rate of treatment group was 93.9%and the control group was 83.3%. there were statistical difference in total effective rate and adverse effect between the two groups（P〈0.05）. Conclusion： There was good effect for azithromycin on the treatment of pediatric mycoplasma pneumonia with less adverse effects. It was better than erythromycin, and worthy of promotion on clinic.