鱼腥草注射液与其药材挥发油相关组分的分析

Analysis of Related Volatile Constituents in Houttuynia Cordata Injection and Its Raw Material Herb

利用GC-MS提供的二维化学数据信息,通过多组分波谱相关色谱方法及化学计量学分辨技术,对中试生产的鱼腥草注射液及其对应的药材挥发性成分进行比较和归属分析。结果表明,在药材和注射液图谱的40个峰族中,只有5个非相关峰族,即在药材制成成品注射液过程中,尽管大量组分出现了浓度消长的现象,但是成品注射液的绝大部分成分来自药材,其中仅有少数组分出现了消失和生成现象。

The comparison and attribution analysis of volatile oil in Houttuynia cordata injection from pilot production and the corresponding herb were conducted, after the combination of muhicomponent spectral correlative chromatography and chemometric resolution technique, based on the two-dimensional data from hyphenated chromatography GC-MS. The results showed that there were only 5 nonrelated Peaks among 40 Peaks of the injection and herb spectrochromatograms. That is, although the concentration of a large number of components fluctuated during the injection production process, most of ingredients in finished product injection came from the raw material herb. Only a very small number of components disappeared and occurred.