2型糖尿病合并冠心病患者的临床特点

Clinical Characteristics of Type 2 Diabetes Mellitus with Coronary Heart Disease

目的分析2型糖尿病患者并发冠心病的临床特点，为临床预防和治疗糖尿病并发冠心病提供依据。方法选取行冠状动脉造影术患者为研究对象，其中2型糖尿病并发冠心病患者46例作为观察组；2型糖尿病不合并冠心病患者30例为对照I组；无糖尿病的冠心病患者50例为对照Ⅱ组。比较各组患者的一般情况、血糖、血压、血脂、糖化血红蛋白（HbAlc）和胰岛素敏感指数（ISI）；并对观察组与对照Ⅱ组患者冠脉造影结果进行对比。结果高血压、HbAlc、甘油三酯（，IIG）、低密度脂蛋白胆固醇（LDL-C）、ISI与糖尿病患者发生冠心病存在相关关系；糖尿病合并冠心病患者以3支病变多见。结论2型糖尿病患者致动脉粥样硬化的因素多而复杂，临床应针对上述因素加强综合观察与治疗。

Objective To investigate the characteristic of type 2 diabetes （T2DM） patients with coronary heart disease （CHD）, and provide methods for prevention and treatment for patients who suffered from CHD. Methods The hospitalized patients were divided into three groups. The treatment group contains 46 cases who were T2D with CHD;The control group I contains 30 cases who were T2DM without CHD;The control group 11 contains 50 eases who were CHD without T2DM. Their ordinary circumstances were compared; the blood sugar, BP, TC, TG, HDL, LDL,HbAle ,C-P ,Ins were measured. Insulin sensitive index（ISI） was calculated. Results Three groups had obvious statistical differences in BP, TC, LDL-C, ISI, HbAle. Diabetic patients with CHD have more common with three lesions. Conclusion In the clinical job, the composite observation should be strengthened and treatment because the factors of atherosclerosis in T2DM patients were numerous and complex.