致病杆菌和发光杆菌抗菌代谢产物研究进展

Advances in Antimicrobial Metabolites of the Symbiotic Bacteria Associated with Entomopathogenic Nematodes

致病杆菌Xenorhabdus和发光杆菌Photorhabdus是昆虫病原线虫肠道共生细菌,具有对宿主昆虫致病和对寄主线虫共生的双重特性,是一类特殊的生防细菌资源,其代谢产物具有广泛的杀虫和抑菌功能。本文综述了近年来昆虫病原线虫共生细菌产生的抗菌物质、编码抗菌代谢产物的基因及抗菌机制的研究进展。

Xenorhabdus and Photohabdus are entomopathogenic bacteria （EPB） which are classified taxonomically in the family of Enterobacteriaceae and possess pathogenicity to insects and symbiotic association with nematodes. Metabolites from these bacteria are insecticidal as well as antimicrobial against a variety of competitor organisms and have broad application prospects in agriculture. This review focuses on advances in identification, encoding genes and antibiotic mechanisms of the antimicrobial metabolites.