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Ⅱ型跨膜丝氨酸蛋白酶4与肠癌 被引量:1

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摘要 跨膜丝氨酸蛋白酶(TMPRSSs),又名II型跨膜丝氨酸蛋白酶(135Ps)是一类定位于细胞膜上具有保守丝氨酸蛋白酶结构域的蛋白家族。Ⅱ型跨膜丝氨酸蛋白酶4(TMPRSS4)Ⅱ型跨膜丝氨酸蛋白酶中的新成员,本文就TMPRSS4的结构及其与肠癌之间的关系做一综述。
作者 朱海峰
出处 《医学信息》 2011年第21期523-523,共1页 Journal of Medical Information
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参考文献6

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同被引文献24

  • 1史忠诚,李钰,张贵寅.Ⅱ型跨膜丝氨酸蛋白酶4与肿瘤[J].国外医学(遗传学分册),2005,28(3):152-155. 被引量:2
  • 2Hooper JD, Clements JA, Quigley JP, et al. Type II trans- membrane serine proteases: insights into an emerging class of cell surface proteolytic enzymes. J Biol Chem, 2001,276 (2) : 857-860.
  • 3Wallrapp C, Hahnel S, Muller-Pillasch F, et al. A novel transmembrane serine protease (TMPRSS3)overexpressed in pancreatic cancer. Cancer Res, 2000,60 (10) : 2602-2606.
  • 4Rawlings ND, Barrett AJ. Families of serine peptidases. Methods Enzymol, 1994,244 : 19-61.
  • 5Liang B, Wu M, Bu Y,et al. Prognostic value of TMPRSS4 expression in patients with breast cancer. Med Oncol, 2013, 30(2) :497.
  • 6Kebebew E, Peng M, Reiff E, et al. ECM1 and TMPRSS4 are diagnostic markers of malignant thyroid neoplasms and improve the accuracy of fine needle aspiration biopsy. Ann Surg, 2005,242(3) : 353-363.
  • 7Nguyen TH,Weber W, Havari E,et al. Expression of TM- PRSS4 in non-small cell lung cancer and its modulation by hypoxia. Int J Oncol, 2012, 41(3):829-838.
  • 8Larzabal L, Nguewa PA, Pio R, et al. Overexpression of TMPRSS4 in non-small cell lung cancer is assoeiated with poor prognosis in patients with squamous histology. Br J Cancer, 2011,105(10) :1608-1614.
  • 9Kim MS, Kuppireddy SV, Sakamuri S, et al. Rapid charac- terization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs). J Proteome Res, 2012, 11 (11): 5556-5563.
  • 10Saramaki OR, Harjula AE, Matikainen PM, et al. TM- PRSS2 : ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis. Clin Cancer Res, 2008,14 (11) : 3395-3400.

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