肥胖对急性胰腺炎发病的影响探讨

The effect of obesity on acute pancreatitis on

目的：探讨肥胖对急性胰腺炎发病的影响。方法：选择急性胰腺炎患者116例，测定体重指数（BMI）、血脂水平、C反应蛋白（CRP），观察APACHEII评分和CT严重指数（CTSI）。结果：肥胖组（BMI≥28kg／m^2）共有54例，非肥胖组（BMI〈24kg／m^2）有62例。肥胖组重症急性胰腺炎（SAP）患病率及病死率高于非肥胖组（P〈0．05）；肥胖组患者BMI和血三酰甘油高于非肥胖组；CRP、APACHEII评分和CT严重指数（CTSI）也高于非肥胖组（P〈O．05）。结论：肥胖与SAP患病率及病死率密切相关。

Objective：To investigate the roles of obesity on the development of acute pancreatitis（AP）. Methods.. 116 patients with acute pancreatitis（AP） were observed in this study. Obesity was evaluated by measurement of body mass index （BM I）. The levels of serum triglyceride and CRP were also measured. Data associated to APACHE II and CTSI scoring system were recorded. Results： There were 54 patients in group 1 （BMI〉26 kg/m^2 obese） ;62 in group 2（BMI≤26kg/m^2 , normal or low weight ）. The incidence , mortality,Serum triglyceride and CAP in group 1 was significantly higher than that in group 2. The value of APACHE 11 and CTSI in group 1 was also higher than that of the other group（P〈0.05）. Conclusions：Our study suggested that obesity was associated with increased incidence and mortality of the AP.