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帕金森病的药物治疗进展 被引量:7

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摘要 帕金森病(parkinson’s disease,PD)是一种常见的老年神经系统慢性退变性疾病。帕金森病主要病理改变是中脑黑质致密部多巴胺(dapamine,DA)能神经元选择性地凋亡,使黑质-纹状体通路DA释放减少,从而导致基底节神经核团调节功能的紊乱,在临床上表现为静止性震颤、肌张力增高、运动迟缓和姿势不稳等一系列症状。目前PD的病因尚未完全清楚,PD的防治成为国内外热点研究课题之一。近年来不断有新的治疗药物出现,用于PD的不同阶段治疗,现就帕金森病的药物治疗进展做一综述。
出处 《卒中与神经疾病》 2011年第5期320-320,F0003,F0004,共3页 Stroke and Nervous Diseases
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