中心性渗出性脉络膜视网膜病变的治疗

The treatment of central exudative chorioretinopathy

中心性渗出性脉络膜视网膜病变（CEC）也称为特发性脉络膜新生血管，多见于中青年，表现为黄斑区孤立的脉络膜新生血管（CNV）。CNV可引起黄斑部的反复出血、渗出、瘢痕形成，严重影响患者的中心视力。该病病因不明，治疗主要针对CNV，目前临床治疗CEC的方法主要有：光动力疗法（PDT）、抗血管内皮生长因子（VEGF）类药物、糖皮质激素类药物、联合治疗、经瞳孔温热疗法（TTT）、激光治疗、放射治疗、手术治疗、中医治疗及基因治疗。就各种治疗方法及其机制等进行综述。

Central exudative chorioretinopathy （CEC） , also known as idiopathic choroidal neovascularization （ICN）, was more common in middle-aged, appearing the isolated macular choroidal neovascularization lesions （CNV）. CNV can cause macular hemorrhage, exudativeing and scarring and therefore affect the patient＇ s central vision. The etiology of CEC is below understanding,and the treatment aimed at CNV. The clinical management of CEC include photodynamic therapy （PDT） , the administration of antibody of vascular epithelial growth factor （VEGF） , adrenal glucoeorticoid drug, combined therapy, transpupillary thermotherapy （TTT）, laser photocoagulation, ratiotherapy, surgery, Chinese traditional medicine and gene therapy. The various treating approaches and their mechanisms were reviewed.