摘要
目的探讨2型糖尿病与乙型肝炎病毒感染的关系。方法采用ELISA法检测588例2型糖尿病患者(DM2组)及同期健康者体检排除糖尿病者604例(对照组)乙型肝炎病毒血清学标志物并比较阳性率。结果 DM2组乙型肝炎表面抗原阳性102例,阳性率17.35%,对照组阳性76例,阳性率12.58%,2组比较差异有统计学意义(χ2=5.324,P=0.021);乙型肝炎表面抗体阳性率DM2组(59.52%)低于对照组(68.21%),差异有统计学意义(χ2=9.753,P=0.002);2组乙型肝炎e抗原、乙型肝炎e抗体阳性率比较差异无统计学意义(P=0.556,P=0.210);乙型肝炎核心抗体阳性率DM2组(51.02%)高于对照组(44.37%),差异有统计学意义(χ2=5.281,P=0.022)。结论糖尿病发生与HBV感染具有一定相关性。
Objective To explore the relationship between hepatitis B virus infection and type 2 diabetes mellitus. Methods A total of 588 cases of type 2 diabetes mellitus and 604 controls were detected serological markers of hepatitis B virus with ELISA to compare the positive rate of serum markers of hepatitis B virus. Results The positive rates of hepatitis B surface antigen were 17. 35% (102/588) and 12. 58% (76/604) in diabetic group and control group, which showed a significant difference between two groups(x2=5. 324, P=0. 021). The positive rates of hepatitis B surface antibodies were 59.52% and 68.21% in diabetic group and control group, which showed a significant difference between two groups(x2=9. 753, P=0. 002). There were no significant differences in hepatitis B e antigen or hepatitis B e antibody between two groups (P=0. 556, 0. 210). The positive rates of hepatitis B core antibody were 51. 02% and 44. 73% in diabetic group and control group, which showed a significant difference between two groups(x2= 5. 281, P = 0. 022). Conclusion Diabetes mellitus is correlated with hepatitis B virus infection.
出处
《中华实用诊断与治疗杂志》
2011年第11期1085-1087,共3页
Journal of Chinese Practical Diagnosis and Therapy
关键词
2型糖尿病
乙型肝炎病毒
血清标志物
乙型肝炎表面抗原
Type 2 diabetes mellitus
hepatitis B virus
serological markers
hepatitis B virussurface antigen