香港大学小儿外科实验室见闻
摘要
2007年6月,受香港大学玛丽医院小儿外科的邀请,我到香港大学李嘉诚医学院小儿外科实验室从事研究助理工作。该实验室是玛丽医院小儿外科研究中心。回顾在这里4年的工作学习经历,我收益良多。小儿外科实验室不仅是人才培养和教育的基地,也是国际交流与协作的平台。其成熟的管理模式、良好的实验条件和丰厚的学术成果,使该实验室研究水平走在世界小儿实验外科的前列。现向国内小儿外科同仁做简要介绍,旨在增进了解,促进交流。
出处
《中华小儿外科杂志》
CSCD
北大核心
2011年第11期867-869,共3页
Chinese Journal of Pediatric Surgery
参考文献12
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1Lui VC, Cheng WW, Leon TY, et al. Perturbation of hoxb5 signaling in vagal neural crests down-regulates ret leading to intestinal hypoganglionosis in mice. Gastroenterology, 2008, 134(4) : 1104-1115.
-
2Garcia-Barcelo MM, Sham MH, Lui VC, et al. Chinese patients with sporadic Hirschsprung's disease are predominantly represented by a single RET haplotype. J Med Genet, 2003,40 (11):e122.
-
3Gareia-Bareelo M, Sham MH, Lui VC, et al. Association study of PHOX2B as a candidate gene for Hirschsprung's disease. Gut, 2003,52 (4) : 563-567.
-
4Gareia-Bareelo M, Ganster RW, Lui VC, et al. TTF-1 and RET promoter SNPs: regulation of PET transcription in Hirschsprung's disease. Hum Mol Genet,2005,14(2) : 191-204.
-
5Gareia-Bareelo MM, Tang CS, Ngan ES, et al. Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Proc Natl Aead Sei USA, 2009, 106 (8) : 2694-2699.
-
6Emison ES, Gareia-Barcelo M, Griee EA, et al. Differential contributions of rare and common, coding and noncoding ret mutations to multifactorial Hirschsprung disease liability. Am J Hum Genet,2010,87(1) :60-74.
-
7Garcia-Barcelo MM, Yeung MY, Miao XP, et al. Genome wide association study identifies a susceptibility locus for biliary atresia on 10q24. 2. Hum Mol Genet,2010, 19(14):2917-2925.
-
8Ngan ES, Garcia-Barcelo MM, Yip BH, et al. Hedgehog/ Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung disease in mice and humans. J Clin Invest, 2011,121 (9) : 3467-3478.
-
9Hao W, Wong OY, Liu X, et al. ω-3 fatty acids suppress inflammatory cytokine production by macrophages and hepatocytes. J Pediatr Surg,2010,45(12) :2412-2418.
-
10李龙,Vincent Lui,Mai Har Sham,谭广.Cdx1和Cdx2基因表达异常与先天性结肠性肠炎的关系[J].中华小儿外科杂志,2003,24(5):406-408. 被引量:9
二级参考文献9
-
1Duprey P,Chowdhury K, Dressler GR, et al. A mouse gene homologous to the Drosophila gene caudal is expressed in epithilial cells from the embryonic intestine .Genes, 1988,2:1647.
-
2James R, Kazenwadel J.Homeobox gene expression in the intestinal epithelium of adult mice .J Biol Chem,1991,266:3246.
-
3Gershon MD. Genes and linesges in the formation of the enteric nervous system. Curr Opin Neurobio, 1997,17:101.
-
4Caneiro P. Enteroclitis in Hirschsprung's disease. Pediatr Surg Int,1992,7:356.
-
5Wilson-Storey D, Scobie WG. Impaired gastrointestinal mucosal defense in Hirschsprung's disease: A due to the pathogenesis of enterocolitis? J Pediatr Surg, 1989,24:462.
-
6Thomas DFM, Fernie DS, Bayston R. Enterocolitis in Hirschsprung's disease: a controled study of the etiologic role of Clostridium difficile. J Pediatr Surg, 1986,21 : 22.
-
7Mallo GV, Rechreche H, Grigerio JM. Molecular cloning, sequencing and expresssion of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis. Int J Cancer, 1997,74:35.
-
8Gershon MD. The enteric nervous system: a second brain. Hosp Practice, 1999,15:31.
-
9Teich S, Schisgall RM, Anderson KD. Ischemic enterocolitis as a complication of Hirschsprung' s disease. J Pediatr Surg, 1986, 21:143.
共引文献8
-
1李龙,付京波,余奇志,刘刚,黄柳明,刘宝富,雷宇,王淑芹,贾钧,王平.直肠粘膜及内括约肌切除对预防巨结肠根治术后肠炎的影响[J].临床小儿外科杂志,2004,3(3):161-164. 被引量:15
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2钭金法,钱云忠,熊启星,李民驹,章希圣,汤宏峰,顾伟忠,项志英,卢红莲,冯志刚,朱雄凯.324例肠神经元发育异常患儿病理特点与术后并发症关系分析[J].中华外科杂志,2006,44(7):463-466. 被引量:22
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3陈业芸,闭永浩.以气腹为主要表现的肠神经元发育异常症2例分析[J].中国误诊学杂志,2008,8(6):1493-1494.
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4吴晓娟,魏明发,冯杰雄.先天性巨结肠并发小肠结肠炎发病机制的研究进展[J].中华小儿外科杂志,2008,29(3):184-186. 被引量:8
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5莫丹,王红.先天性巨结肠相关性小肠结肠炎研究进展[J].实用儿科临床杂志,2008,23(7):542-544. 被引量:4
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6李龙,刘树立,付京波,张军,侯文英,刘刚,黄柳明,王淑芹,贾钧.经肛门直肠黏膜及内括约肌切除术治疗先天性巨结肠的技术要点和疗效[J].中华小儿外科杂志,2008,29(9):515-518. 被引量:12
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7赵萍,张钦明,李现令.先天性巨结肠小肠结肠炎病因学研究[J].中华小儿外科杂志,2009,30(6):404-406. 被引量:1
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8魏明发,王果,朱珉,易斌,王小林,韩杰,史慧芬.先天性巨结肠症RET和EDNRB基因的突变[J].世界华人消化杂志,2004,12(3):635-638. 被引量:5
-
1廖光珍.哪些幼儿不易得哮喘[J].家庭·育儿,2002,0(2):59-59.
-
2中国-香港小儿腹腔镜学习班通知[J].临床小儿外科杂志,2008,7(1).
-
3祁沛.不同剂量复方丹参注射液佐治新生儿硬肿症疗效观察[J].山西中医,2007,23(1):27-28. 被引量:1
-
4杨于嘉,姚裕家,钟乐.第三届全国新生儿脑损伤专家研讨会会议纪要[J].中国当代儿科杂志,2005,7(1). 被引量:1
-
5时保军.日本儿童医院研修见闻及日本小儿外科现状[J].中华小儿外科杂志,1999,20(5):318-319.
-
6宋亚君.日本新生儿重症监护病房研修见闻[J].中华儿科杂志,2000,38(6):395-395. 被引量:1
-
7罗春华,廖清奎.进一步提高小儿特发性血小板减少性紫癜的研究水平[J].中华儿科杂志,1999,37(1):5-6. 被引量:16
-
8张天华.切莫忽视儿童副流感[J].家庭医学(上半月),2005(3):15-15.
-
9袁正伟,王维林.首届全国小儿实验外科与临床新技术会议纪要[J].中华小儿外科杂志,2007,28(2):111-112.
-
10大陆-香港小儿微创外科学习班的通知[J].腹腔镜外科杂志,2014,19(1):80-80.