不同口服补液方法预防运动性横纹肌溶解症的对比研究

Different oral fluid infusion methods for prevention of exertional rhabdomyolosis

目的探讨不同口服补液方法预防运动性横纹肌溶解症的效果。方法入伍新战士90名随机分为3组进行3 000m越野跑,每组各30人。越野跑过程中给予不同补液方法,A组饮用白开水,B组饮用口服补液盐,C组饮用口服补液盐+苏打水,对三组不适症状、生化指标等进行对比。结果运动结束时,口渴症状比例B组、C组均低于A组,但只有C组与A组差异有统计学意义(P<0.05);运动后12h,C组血清肌红蛋白、肌酸激酶和乳酸脱氢酶水平均低于A组,B组肌红蛋白也低于A组(P<0.05)。C组肌酸激酶和乳酸脱氢酶水平低于B组(P<0.05)。结论剧烈运动中饮用口服补液盐和苏打水可能有预防运动性横纹肌溶解症的作用。

Objective To study the different oral fluid infusion methods for prevention of exertional rhabdomyolosis（ERB）.Methods Ninety new-enlisted soliders were randomly divided into groups A,B and C（30 in each group） and had a 3 000m cross-country race,during which the soliders in 3 groups drank boiled water,salt water,and salt water plus soda water,respectively.Then,their uncomfortable symptoms and biochemical indexes were compared.Results The thirst level was lower in groups B and C than in group A.However,the thirst level was significantly lower in group C than in group A（P〈0.05） after the race.The levels of serum myohemoglobin,creatine kinase and lactic dehydrogenase were lower in group C than in group A（P〈0.05）,while the level of serum myohemoglobin was lower in group B than in group A,and the levels of creatine kinase and lactic dehydrogenase were lower in group C than in group B 12h after the race（P〈0.05）.Conclusion Drinking oral salt water and soda water can prevent ERB during strenuous exercise.