中西医结合治疗重症急性胰腺炎的临床研究

Clinical study of integrated TCM-WM on treating severe acute pancreatitis

目的:探讨中西结合治疗重症急性胰腺炎(severe acute pancreatitis,SAP)的方法与疗效。方法:基础疗法及大黄、芒硝胃管注入和芒硝外敷等中药治疗。结果:治疗组25例中,治愈18例(72%),显效2例,转手术治疗3例,死亡2例,病死率为8%,与对照组比较,差异有显著性(P<0.05),其死亡原因为急性呼吸窘迫综合征和全身多脏器衰竭,平均住院20.7天,与对照组比较,差异有显著性(P<0.05)。结论:该方法能显著提高SAP治愈率,降低病死率,减少平均住院天数,经济安全,使用方便,值得推广。

Objective：to investigate the therapeutic method and clinical effect with integrated traditional Chinese medicine and Western medicine（TCM-WM） on treating severe acute pancreatitis.Methods：To use the basic therapy and Chinese herbal therapy including rhubarb and mirabilite by gavage and external application of mirabilite.Results：Among 25 cases in the TCM-WM group,18 cases were cured（72%）,2 cases were obviously improved,3 cases were converted to surgical treatment,2 cases died with the mortality rate of 8%.There were significant differences between the TCM-WM group and the control group（P0.05）.The main causes of the death cases were ARDS and multiorgan failure with the average hospital stay of 20.7d,which also showed significant differences between the TCM-WM group and the control group（P0.05）.Conclusion：This method contributes a lot in improving the cure rate,reducing the mortality and shortening average hospital stays on severe acute pancreatitis,with safety,convenience and economy,and deserves the clinical promotion.