急性心肌梗死患者合并抑郁状况及相关因素分析

Depression state and relevant factors of patients with acute myocardial infarction

目的了解急性心肌梗死3个月以上患者合并抑郁的状况，探讨其相关因素。方法采用电话回访的方式，应用Zung氏抑郁自评量表（SDS），对从本院心内监护入院后出院3-18个月的确诊急性心肌梗死的患者共105例进行问卷调查。结果急性心肌梗死后患者抑郁的发病率是21．9％，单因素分析显示抑郁及非抑郁患者在年龄、既往有高血压病史、出院后发生过心绞痛等方面的差异有统计学意义（P〈0．05）。通过多因素分析显示年龄与急性心肌梗死后抑郁的发生相关（OR．=1．067，95％可信区间1．002—1．137），将年龄与抑郁总分进行相关分析显示二者呈正相关（r=0．439，P〈0．01），年龄越大，抑郁程度越严重。结论急性心肌梗死后患者抑郁发生率较高，年龄是抑郁发生的重要危险因素。

Objective To investigate depression state in patients after acute myocardial infarction for more than 3 months and analyze the relevant factors. Methods The Zung SDS and general data questionnaire were systematically applied by to the 105 patients after acute myocardial infarction for 3 - 18 months by telephone visit. Results Among patients after acute myocardial infarction for more than 3 months, the incidence of depression was 21.9%. Age, history of hypertension, and occurrence of angina after discharges were different in the depression and non-depression patients after myocardial infraction on univariate analysis （ P 〈 0. 05 ）. Multiple logistic regression analysis identified age as an independent depression predictor after acute myocardial infraction for more than 3 months （ OR = 1. 067, 95% CI： 1. 002 - 1. 137）, and the incidence of depression were positively associated with age of patients by correction analysis （r = 0. 439, P = 0. 000）. Conclusions Patients after acute myocardial infarction for long time were still susceptible to depression. Age was the independent risk factor of depression ＇for patients with long term after acute myocardial infraction.