摘要
诱导性多能干细胞(iPS)是一种类似胚胎干细胞的新型干细胞。iPS细胞可以从各种不同动物的不同体细胞转化而来,它可以分化为心房肌、心室肌、血管以及传导系统的细胞。iPS细胞或由iPS细胞分化来的心肌细胞可用来治疗心肌梗死。通过iPS技术建立细胞模型可研究长QT综合征(LQTS)、Brugada综合征、致右室心律失常性心肌病(ARVC)等遗传性心脏病的发病机制。
出处
《国际心血管病杂志》
2011年第6期365-368,共4页
International Journal of Cardiovascular Disease
基金
国家自然科学基金(30871077)
江苏省普通高校研究生科研创新计划(81170160)
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