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尿纤维连接蛋白用于诊断膀胱癌的研究进展 被引量:1

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摘要 纤维连接蛋白(fibmnectin,FN)是1974年研究发现的一种具有多生物学功能的高分子糖蛋白。1992年沈周俊首次通过测定尿FN来诊断膀胱移行细胞癌(bladder transitional cell carcinoma,BTCC),其后,尿FN在泌尿系肿瘤诊断和治疗方面的研究取得了较快发展。尿FN对BTCC的诊断有较高的灵敏度与特异度,它作为BTCC新的诊断标志物是当今基础研究的热点。本文就尿FN在BTCC诊断和治疗方面的研究进展和l临床应用作一综述。
出处 《国际泌尿系统杂志》 2011年第6期757-760,共4页 International Journal of Urology and Nephrology
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参考文献18

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二级参考文献4

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共引文献24

同被引文献22

  • 1沈周俊,丁国庆,吴金艳,余燕岚,陆静,陈善闻,陈军.膀胱内灌注纤维蛋白溶解抑制药物对卡介苗抗膀胱癌复发作用影响的临床研究[J].中华泌尿外科杂志,2006,27(1):25-28. 被引量:6
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  • 8Coon BG,Crist S,González-Bonet AM,et al.Fibronectin attachment protein from bacillus Calmette-Guerin as targeting agent for bladder tumor cells.Int J Cancer,2012,131:591-600.
  • 9Pan CW,Shen ZJ,Wu TT,et al.Cell adhcsion to fibronectin induces mitomycin C resistance in bladder cancer cells.BJU Int,2009,104:1774-1779.
  • 10Raitanen MP,Aine R,Rintala E,et al.Differences between local and review urinary cytology in diagnosis of bladder cancer:an inter-observer multi-center analysis.Eur Urol,2002,41:284-289.

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