红花佐治重症急性胰腺炎肝损伤的临床研究

Efficacy of Honghua injection in treatment of hepatic injury of severe acute pancreatitis

目的探讨红花注射液在重症急性胰腺炎(severe acute pancreatitis,SAP)肝损伤治疗中的应用价值。方法17例SAP肝损伤患者采用传统治疗的同时予红花注射液静脉滴注,观察患者肝功能的变化及预后。结果治疗后患者APACH EⅡ评分、血淀粉酶及C-反应蛋白下降,肝功能明显改善(P均<0.05),病死率为17.65%。结论早期应用红花注射液治疗SAP肝损伤,可改善其病情,降低病死率。

Objective To investigate the efficacy of Honghua injection in treatment of hepatic injury of svere acute pancretitis（SAP）. Methods Totally 17 patients with hepatic injury of SAP were involved, Honghua injection were provided with intravenous drip on the basis of taditional therapies. We observed the level of liver function and prognosis. Results After treatment, acute phsiology and chronic health evaluaion （ APACHE Ii ）, serum amylase arLd C recative protein were decreased, in addition, the level of liver function were improved （P 〈 0. 05）. The mortality rate was 17.65%. Con- clusions Early use of Honghua injection in hepatic injury of SAP may improve the conditions and re- duce the mortality.