冠心病伴发2型糖尿病患者心率变异性分析

Heart rate variability analysis of patients with coronary heart disease and type 2 diabetes

目的观察冠心病合并2型糖尿病患者自主神经功能状态。方法选择2005～2011年在我院行24h动态心电图检查的冠心病及糖尿病患者各30人,冠心病伴发2型糖尿病者30人,健康体检者40人,由计算机自动测出心率变异性时域各项指标。结果冠心病患者或2型糖尿病患者心率变异性指标均低于健康对照组(P<0.05),冠心病合并2型糖尿病患者心率变异性指标低于单一疾病者(P<0.05)。结论冠心病合并2型糖尿病患者自主神经功能损害较重,发生恶性心血管事件几率较大。

Objective To observe the autonomic nerve activity of patients with coronary heart disease and type 2 diabetes.Methods The observed object include 30 cases with coronary heart disease,30 cases with diabetes,30 cases with coronary heart disease and type 2 diabetes,40 healthy cases.The heart rate variability in time domain indexes were measured automatically By the computer.Results The heart rate variability indexes of cases with coronary heart disease or type 2 diabetes were lower than healthy persons（P〈0.05）.The heart rate variability indexes of cases with coronary heart disease and type 2 diabetes were lower than single disease（P〈0.05）.Conclusion The autonomic nerve activity damage of patients with coronary heart disease and type 2 diabetes is heavier,the occurrence of cardiovascular events are more likely.