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血管紧张素转化酶抑制剂在慢性心力衰竭中的应用 被引量:7

Angiotensin-converting enzyme inhibitors in the treatment of chronic heart failure
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摘要 慢性心力衰竭(CHF)的治疗目标不仅仅是改善症状、提高生活质量,更重要的是延缓和防止心室重构发展,降低CHF死亡率和住院率,目前临床药物治疗仍居主导地位。血管紧张素转化酶抑制剂(ACEI)一直是CHF治疗的一线药物,血管紧张素Ⅱ受体阻断剂(ARB)对CHF预后也有益,但与ACEI相比,其并无显著优势。本文综述ACEI在CHF治疗中的临床地位。 The target of chronic heart failure(CHF)treatment is not only to improve the symptoms and life quality,but also to delay or prevent from the myocardial reconstruction development in order to decrease the mortality and hospitalization rate.Drug therapy is still the major strategy for CHF.Angiotensin-converting enzyme inhibitors(ACEIs) are always the first-line drugs in the treatment of CHF.Recently,angiotensin Ⅱ receptor blockers(ARBs) have been demonstrated to improve the prognosis of CHF,but there is no much superiority compared with ACEIs.This review discusses the clinical application of ACEIs for CHF.
作者 李新立 周芳
出处 《世界临床药物》 CAS 2011年第11期659-662,共4页 World Clinical Drug
关键词 慢性心力衰竭(CHF) 血管紧张素转化酶抑制剂(ACEI) 血管紧张素Ⅱ受体阻断剂(ARB) chronic heart failure(CHF) angiotensin-converting enzyme inhibitor(ACEI) angiotensin Ⅱ receptor blocker(ARB)
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参考文献18

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二级参考文献65

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