摘要
目的探讨冷空气活动对人群血脂水平的影响,为冷空气对心脑血管疾病影响的防治提供依据。方法收集甘肃省某市2010年10月22—25日、2010年12月4—6日两次冷空气过境前后资料。分别于冷空气过境前、过境期间对68名研究对象进行总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、极低密度脂蛋白胆固醇(VLDL-C)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)检查,分析血脂相关指标水平在冷空气过境前及期间的变化。结果气候资料显示两次冷空气过程类型分别为中等强度冷空气、弱冷空气;第一次冷空气过境期间HDL-C和ApoA1均较过境前有显著性降低,差异有统计学意义(P<0.05,P<0.01);第二次冷空气过境期间TG、VLDL-C均较过境前有显著性升高,差异有统计学意义(P<0.05);其余血脂相关指标水平无显著性差异(P>0.05)。结论冷空气对血脂部分相关指标水平有一定的影响,可能是造成冷空气致心脑血管疾病发作的主要危险因素之一。
Objective To explore the effects of cold air activity on blood lipids level of population, and provide the basis for preventing the cardiovascular and eerebrovascular diseases. Methods The climate data were collected before and after cold air passing in Gansu province. The blood lipids levels were measured in 68 subjects before and during the cold air transit. The lipid indexes detected were total cholesterol (TC), triglyeerides (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein eholesterol(LDL-C), very low density lipoprotein cholesterol(VLDL-C), apolipoproteinAl(ApoA1), apolipoprotein B (ApoB). Results The climate data showed that the two cold air processes were moderate strength and weak cold air. HDL-C and ApoA1 after the first cold air process were significantly decreased compared with those before the cold air process (P〈0.05, P〈0.01); When the second cold air passing, TG and VLDL-C increased significantly than those before that (P〈0.05). Conclusion Cold air can impact some lipids level of population, which may be one of a possible risk factors for cardiovascular and cerebrovascular disease attack.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2011年第11期953-955,共3页
Journal of Environment and Health
基金
国家自然科学基金面上项目(40975069)
中央高校基本科研业务费专项资金(lzujbky-2010-139)
公益性行业(气象)科研专项经费(GYHY201106034)资助
关键词
气象
冷空气
血脂
Weather
Cold air
Blood lipids level