鼻咽癌的放化疗现状

Concurrent status of chemotherapy and radiotherapy of nasopharyngeal carcinoma

调强放疗（IMRT）在剂量学和放射生物效应方面较传统放疗技术具有优势，已成为鼻咽癌放疗的主流。中晚期鼻咽癌单纯放疗的疗效较差，放化疗综合治疗可显著提高疗效。目前同步放化疗逐渐成为局部晚期鼻咽癌的标准治疗模式，但诱导化疗和辅助化疗的价值及其与同步放化疗之间的不同组合模式有待明确。

Intensity-modulated radiation therapy （IMRT）is a more advanced radiotherapy technique than routine radiotherapy, and has been effectively utilized in the treatment of nasopharyngeal carcinoma （NPC）. Rradiotherapy alone has disappointing effect to local advanced cases. Nevertheless, chemoradiotherapy provides long term survival. Chemoradiotherapy is becoming the standard therapeutic regimen for local advanced NPC. But different ways of chemomdiotherapy such as induction, concurrent, adjuvant chemotherapy still need to be defined.