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Th17细胞与哮喘的研究进展 被引量：4

Progress of asthma and Th17 cells
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摘要 支气管哮喘是一种慢性炎症性气道疾病，以往认为辅助性T细胞1（Th1）／Th2比例失衡是哮喘发病的重要机制。近年发现了一种以产生IL—17为主要细胞因子的Th17细胞，在哮喘的发病机制中具有重要作用，IL-17还具有对哮喘的负性调节作用，有可能成为治疗哮喘的有意义的靶目标。 Bronchial asthma is a chronic inflammation airway disease. The imbalance of T helper cell （Th） 1/Th2 immunity plays an important role in the pathogenesis of allergic asthma. Recent years a new T cell lineage has been recognized as Th17 cells because they can produce cytokines interleukin-17. The new studies find that interleukin-17 is a negative regulator of asthma, and interleukin-17 or Th17 cells may represent an interesting therapeutic target in asthma.
作者 胡岩岩（综述） 王亚亭（审校）
机构地区 安徽医科大学第一附属医院儿科
出处 《国际儿科学杂志》 2011年第6期579-582,共4页 International Journal of Pediatrics
关键词 支气管哮喘 TH17细胞 IL-17 Bronchial asthma Th17 cells Interleukin-17
分类号 R562.25 [医药卫生—呼吸系统]
  • 相关文献

参考文献24

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二级参考文献17

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共引文献25

同被引文献69

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引证文献4

二级引证文献11

国际儿科学杂志
2011年 第6期

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