麻醉药对[Ca2＋]i的多途径改变及相关生物学效应

Multiways of the Anesthetics to Change [Ca2＋]i and Their Related Effects

Ca2＋是细胞内的第二信使．它参与细胞内很多生理活动过程．包括神经递质释放．肌肉收缩，腺体分泌．学习记忆及细胞凋亡等。麻醉药可以通过多种方式直接或间接改变[Ca2＋]i从而对生物体产生错综复杂的影响．这些影响有些与麻醉作用有关有些与麻醉作用无关。

Ca2＋ is an intracellular second message, it has been involved in versatile intracellular physiological activities, including neurotransmitter release, muscle contraction, gland secretion, learning and memory, even apoptosis, Anesthetics especially inhalational anesthetics can change [Ca2＋]i directly or indirectly in multiple ways, as a result having the organism complicatedly affected, some of the affection is related with anesthesia, but most is nothing to do with anesthesia.