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脑钠肽与心力衰竭 被引量:3

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摘要 脑钠肽(brain natriuretic peptide,BNP)主要储存于心室肌内,其分泌量随心室充盈压的高低变化,其生理作用为扩张血管,增加排钠,对抗肾上腺素-肾素-血管紧张素-醛固酮系统的水钠潴留效应,心力衰竭(Heart failure,HF)时,心室壁张力增加,心室内BNP分泌增加,使血浆中BNP水平升高,其值与心衰的严重程度呈正相关。为此,血浆BNP水平可作为评定心衰的进程和判断预后的指标。本文通过介绍BNP在国内外的研究进展,论述脑钠肽早期诊断心衰及对各期心衰者严重程度进行危险分层的价值。
作者 于水清 刘敏
出处 《科技信息》 2011年第32期I0062-I0063,共2页 Science & Technology Information
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