抗菌药物在腹腔感染中的合理应用

Rational use of antibacterials for intra-abdominal infections

腹腔感染可分为社区获得性腹腔感染及医院获得性腹腔感染。腹腔感染的常见病原菌有肠杆菌科细菌、厌氧菌、链球菌、肠球菌、非发酵糖革兰阴性菌等。抗菌药物的使用是治疗腹腔感染的关键,抗菌药物的使用应结合腹腔感染的具体部位、严重程度、细菌与药物敏感状态的流行病学现状和抗菌药物的药效学和药代动力学特点等因素,选择合理的品种和正确的给药方法。

Summary：Intra-abdominal Infections include community-acquired infection and health care-associated infection. The pathogenic bacteria commonly include Enterobacteriaceae, anaerobic bacteria, Streptococcus, Enterococcus,non-fermented sugar bacteria, etc. Rational antibacterial chemotherapy is very important for intra-abdominal infections. The theraputic regime should follow the principles of right indication, right antibiotics, right time and right method based on the conditions of patients, degree of infection severity, bacterial susceptibility, pharmacody- namics,pharmacokinetics and so on.