自然感绵羊慢性病毒对新疆卡拉库尔羊品种敏感性研究

Study on Natural Infection with Ovine Lentivirus in Xinjiang Karakul Sheep

【目的】用绵羊进行性肺炎病毒((OPPV)实验感染新疆卡拉库尔羊,为证实新疆卡拉库尔羊对OvLV美国株(OPPV)的敏感性很低,且呈现亚临床性感染。【方法】琼扩试验(AGID)检查血清OvLV抗体和进行病理组织学检查,以确定是否有特征性病变的靶器官。【结果】只有33%的受试羊在首次检查时出现内线和外线,乳腺是最敏感的靶器官,其次是肺。【结论】通过对自然感染绵羊慢性病毒新疆株的新疆卡拉库尔羊的研究,证实了新疆卡拉库尔羊是对OvLV的低敏感性品种。

[ Objective ] The research has been conducted to prove whether the Xinjiang Kalakul sheep were infected by ovine progress pneumonia virus （oppv） low sensitivity to ovlv with American strain （oppv） and through experiments. Xinjiang Kalakul sheep has a appeared infected. [ Method ] The test of agar gel immunodiffusion was used to check antibody of ovlv and pathohistology examination was applied to prove characteristic pathological changes of the target organ. [ Result ] Merely 33% sheep for experiment were examined to have inline and outline in the first time. Mammary gland is the most sensitive target organ, and the second sensitive organ is lungs. [ Conclusion ] This program, for the first time, through the long - term research into sheep that were naturally infected with ovine lentivirus Xinjiang strain, proved that Xinjiang Kalakul sheep are hyposensitivity breed to ovlv.