早发型重度子痫前期发病对妊娠结局的影响

The affect of early onset severe preeclampsia on pregnancy outcome

目的:分析早发型重度子痫前期(EOSP)发病时间对妊娠结局的影响,探讨期待保守治疗EOSP的临床意义。方法:将71例EOSP按发病时孕周分为A组(孕28～31+6周)28例和B组(孕32～34周)43例,比较两组发病孕周、终止妊娠孕周、孕周延长时间、严重并发症发生情况、胎儿及新生儿病死率。结果:围生儿病死率A组为21.4%,B组为11.4%;孕产妇并发症发生率A组为65.6%,B组为为51.3%;组间比较差异有统计学意义(P<0.05)。结论:早发型重度子痫前期发病孕周越早,新生儿死亡率越高;短期的保守治疗可有效延长孕周,改善围生儿预后。

Objective：To analyze the affect of the onset time of early onset severe preeclampsia（EOSP） on pregnancy outcome,and to study the clinical significance of conservative expectations treatment of EOSP.Methods：71 cases EOSP were divided into group A（28 to 31 ＋6 weeks,28 patients） and group B（32 to 34 weeks,43 cases） by gestational age at onset.The gestational age at onset,gestational age at termination of pregnancy,extend time of gestational age,the incidence of serious complications,fetal and neonatal mortality were compared Results：The mortality of perinatal child was 21.4% in group A and 11.4% in group B;the incidence of maternal complications was 65.6% in group A and 51.3% in group B;the difference between groups was statistically significant（P0.05）.Conclusion：The earlier the gestational age is,the higher the neonatal mortality is for the early onset severe preeclampsia.The short-term conservative treatment can effectively extend the gestational age and improve perinatal outcome.