1Na Liu,Guoyun Zhang,Feng Bi,Yanglin Pan,Yan Xue,Yongquan Shi,Liping Yao,Lina Zhao,Yi Zheng,Daiming Fan.RhoC is essential for the metastasis of gastric cancer[J]. Journal of Molecular Medicine . 2007 (10)
2Zhao L,Wang H,Li J,et al.Overexpression of Rho GDP-disso-ciation inhibitorαis associated with tumor progression and poor prognosis of colorectal cancer. Journal of Proteome Research . 2008
3Heasman SJ,Ridlev AJ.Mammalian Rho GTPases:new insights into their functions from in vivo studies. Nature Reviews Molecular Cell Biology . 2008
4Novick P,Guo W.Ras familytherapy:Rab,Rho and Ral talkto the exocyst. Trends in Cell Biology . 2002
5Han S,Sidell N,Roman J.Fibronectin stimulates human lung carcinoma cell proliferation by suppressing p21 gene expression via signals involving Erk and Rho kinase. Cancer Letters . 2005
6Faried,A,Faried,LS,Kimura,H,Nakajima,M,Sohda,M,Miyazaki,T,Kato,H,Usman,N,Kuwano,H.RhoA and RhoC proteins promote both cell proliferation and cell invasion of human oesophageal squamous cell carcinoma cell lines in vitro and in vivo. European Journal of Cancer . 2006
7Pille,JY,Denoyelle,C,Varet,J,Bertrand,JR,Soria,J,Opolon,P,Lu,H,Pritchard,LL,Vannier,JP,Malvy,C,Soria,C,Li,H.Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo. Molecular Therapy . 2005
8Gadea G,de Toledo M,Anguille C,et al.Loss of p53pro-motes RhoA-ROCK-dependent cell migration and invasion in3D matrices. The Journal of Cell Biology . 2007
9Kleer,CG,Teknos,TN,Islam,M,Marcus,B,Lee,JS,Pan,Q,Merajver,SD.RhoC GTPase expression as a potential marker of lymph node metastasis in squamous cell carcinomas of the head and neck. Clinical Cancer Research . 2006
10Ikoma,T,Takahashi,T,Nagano,S,Li,YM,Ohno,Y,Ando,K,Fujiwara,T,Fujiwara,H,Kosai,K.A definitive role of RhoC in metastasis of orthotopic lung cancer in mice. Clinical Cancer Research . 2004
2Peto J.Cancer epidemiology in the last century and the next decade [J].Nature,2001,411(6835):390-395.
3Jemal A,Siegel R,Ward E,et al.Cancer statistics [J].CA Cancer J Clin,2006,56(2):106-130.
4Deming D,Geiger P,Chen H,et al.ZM336372,a Raf-1 activator causes suppression of proliferation in a human hepatocellular carcinoma cell line [J].J Gastrointest Surg,2008,12(5):852-857.
