期刊文献+

应用液质联用技术对大鼠血浆中槲皮素的测定 被引量:4

Detection of Quercetin and Its Metabolites in Plasma of Rats by LC-MS/MS
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摘要 Liquid chromatography-mass spectrometry(LC-MS) was combined by high resolution of high-liquid chromatography and high sensitivity,high specificity of mass spectrometry,which not only can separate the complicated mixtures,but also doesn’t need more complicated pre-treatment for samples.The qualitative and quantitative analysis of quercetin was implemented by the information of the molecular structure and fragment.In this paper,the LC-MS/MS method was established for determination of quercetin in plasma. Liquid chromatography-mass spectrometry(LC-MS) was combined by high resolution of high-liquid chromatography and high sensitivity,high specificity of mass spectrometry,which not only can separate the complicated mixtures,but also doesn't need more complicated pre-treatment for samples.The qualitative and quantitative analysis of quercetin was implemented by the information of the molecular structure and fragment.In this paper,the LC-MS/MS method was established for determination of quercetin in plasma.
出处 《分析测试学报》 CAS CSCD 北大核心 2008年第S1期19-20,共2页 Journal of Instrumental Analysis
关键词 QUERCETIN LC-MS/MS qualitative and QUANTITATIVE analysis quercetin LC-MS/MS qualitative and quantitative analysis
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参考文献3

  • 1Molden E,Helen Boe G,Christensen H,et al.Highperformance liquid chromatography-mass spectrometry analysis of diltiazem and 11 of its phase I metabolites in human plasma[].Journal of Pharmaceutical and Biomedical Analysis.2003
  • 2Appolpnova SA,Shpak AV,Semenov VA.Liquid chromatography-electrospray ionization ion trap mass spectrometry for analysis of mesocarb and its metabolites in human urine[].Journal of Chromatography B.2004
  • 3Wittig J,Herderich M,Graefe EU,Veit M.Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry[].Journal of Chromatography B.2001

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