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清胰汤保留灌肠对急性重症胰腺炎患者胃肠动力学变化机制的研究 被引量:19

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摘要 【目的】观察清胰汤保留灌肠治疗重症急性胰腺炎(SAP)的临床效果,同时测定血清胃动素(MTL)、胆囊收缩素(CCK)和血管活性肠肽(VIP)的变化,旨在探讨清胰汤保留灌肠治疗SAP的作用机理。【方法】SAP患者36例,随机分成A、B组:A组18例,常规治疗+清胰汤保留灌肠治疗;B组18例,常规治疗;观察患者临床指标变化,动态测定患者血清MTL、CCK、VIP浓度。【结果】A组18例SAP患者症状体征指标变化与B组比较有显著性差异(P<0.01)。A组、B组SAP患者治疗前、后血清MTL、CCK、VIP浓度与正常值相比显著增高(P<0.01),治疗后A、B组患者血清MTL、CCK、VIP浓度变化相比较有显著性差异(P<0.01)。【结论】清胰汤保留灌肠治疗SAP疗效显著,其作用机制可能与调节机体中胃肠激素(胃动素、胆囊收缩素和血管活性肠肽)的水平有关。
出处 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2008年第S2期20-22,共3页 Journal of Sun Yat-Sen University:Medical Sciences
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参考文献11

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